Why Cannabis Works

  • Cannabis has been used for medicinal purposes for at least 5000 years.
  • Cannabis contains over 1200 compounds and 144 cannabinoids.
  • In the early 1960s Professor Raphael Mechoulam isolated the cannabinoid compound of Δ9-tetrahydrocannabinol (THC), the main active principle of cannabis.  However, subsequent research has demonstrated the important role that many other cannabinoids play.
  • In 1988 the endocannabinoid system (ECS) was discovered to exist in all vertebrates on Earth.  Subsequent research has identified CB1 receptors primarily in the brain and central nervous system and CB2 receptors in the immune system throughout the body.
  • In the early 1990s Professor Mechoulam’s team then isolated and identified the endogenous cannabinoids anandamide from the brain and 2-arachidonoyl glycerol (2-AG).
  • Global research has confirmed that the ECS plays an essential role in maintaining normal bodily functions.  The ECS is a homeostatic system that balances those functions to ensure a healthy life.